Michal Heger Selected Research

Liposomes (Liposome)

6/2020	In Vivo Assessment of Thermosensitive Liposomes for the Treatment of Port Wine Stains by Antifibrinolytic Site-Specific Pharmaco-Laser Therapy.
10/2018	Preclinical evaluation of thermosensitive poly(N-(2-hydroxypropyl) methacrylamide mono/dilactate)-grafted liposomes for cancer thermochemotherapy.
1/2017	Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy.
1/2017	Preparation and Practical Applications of 2',7'-Dichlorodihydrofluorescein in Redox Assays.
8/2016	Tranexamic Acid-Encapsulating Thermosensitive Liposomes for Site-Specific Pharmaco-Laser Therapy of Port Wine Stains.
1/2016	Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy.
12/2015	Low-power photodynamic therapy induces survival signaling in perihilar cholangiocarcinoma cells.
6/2009	On the interaction of fluorophore-encapsulating PEGylated lecithin liposomes with hamster and human platelets.

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Michal Heger Research Topics

Disease

17	Neoplasms (Cancer) 09/2022 - 01/2008
11	Inflammation (Inflammations) 01/2019 - 02/2011
11	Ischemia 01/2019 - 12/2011
10	Reperfusion Injury 04/2017 - 12/2011
8	Port-Wine Stain (Nevus Flammeus) 06/2020 - 02/2005
7	Hypoxia (Hypoxemia) 01/2022 - 01/2015
7	Thrombosis (Thrombus) 06/2020 - 02/2005
5	Cholestasis 11/2018 - 10/2010
5	Klatskin Tumor 09/2017 - 12/2015
4	Necrosis 03/2021 - 01/2015
4	Hypertrophy 10/2017 - 01/2008
3	Breast Neoplasms (Breast Cancer) 09/2022 - 08/2015
3	Phototoxic Dermatitis (Phototoxicity) 09/2022 - 09/2017
3	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2017
3	Hypothermia 01/2019 - 01/2015
2	Acute Liver Failure (Fulminant Hepatic Failure) 01/2022 - 02/2016
2	Hyperthermia 06/2020 - 10/2018
2	Hemorrhagic Shock 01/2019 - 07/2012
2	Fatty Liver 09/2014 - 02/2011
2	Hypovolemia 11/2011 - 04/2011
1	Photosensitivity Disorders (Photodermatitis) 09/2022
1	Triple Negative Breast Neoplasms 09/2022
1	Obesity 01/2022
1	Neuroblastoma 01/2021
1	Pancreatic Fistula (Pancreatic Fistulas) 11/2019
1	Adenocarcinoma 08/2019
1	Cholangiocarcinoma 08/2019
1	Edema (Dropsy) 01/2019
1	Septic Shock (Toxic Shock Syndrome) 01/2019

Drug/Important Bio-Agent (IBA)

10	1-phenyl-3,3-dimethyltriazene (PDT)IBA 09/2022 - 08/2015
8	Liposomes (Liposome)IBA 06/2020 - 06/2009
7	Photosensitizing Agents (Photosensitizers)IBA 09/2022 - 12/2015
6	Oxygen (Dioxygen)IBA 01/2018 - 12/2010
5	Zn(II)-phthalocyanine (zinc phthalocyanine)IBA 03/2021 - 12/2015
4	Antifibrinolytic Agents (Antifibrinolytics)IBA 06/2020 - 07/2007
4	Pharmaceutical PreparationsIBA 08/2016 - 02/2005
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 12/2015
3	Transaminases (Aminotransferases)IBA 01/2019 - 11/2016
3	CytokinesIBA 01/2019 - 02/2012
3	Bile Acids and Salts (Bile Acids)IBA 11/2018 - 01/2016
2	zinc tetrasulfophthalocyanineIBA 09/2022 - 03/2021
2	AntioxidantsIBA 01/2022 - 01/2019
2	CurcuminIBA 01/2021 - 01/2014
2	InterleukinsIBA 11/2019 - 02/2011
2	Biomarkers (Surrogate Marker)IBA 08/2019 - 01/2017
2	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2018 - 01/2015
2	Tranexamic Acid (AMCA)FDA Link 08/2016 - 07/2007
2	Hypoxia-Inducible Factor 1IBA 01/2016 - 12/2015
2	Choline (Choline Chloride)IBA 01/2016 - 02/2011
2	Methionine (L-Methionine)FDA Link 01/2016 - 02/2011
2	P-SelectinIBA 01/2015 - 09/2011
2	NitrogenIBA 09/2014 - 04/2012
2	LipidsIBA 02/2011 - 06/2009
1	AluminumIBA 09/2022
1	phthalocyanineIBA 09/2022
1	UbiquitinIBA 05/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	aluminum tetrasulfophthalocyanineIBA 03/2021
1	aluminum phthalocyanineIBA 03/2021
1	Cytostatic AgentsIBA 01/2021
1	MicellesIBA 01/2021
1	LigandsIBA 06/2020
1	C-Reactive ProteinIBA 11/2019
1	Interleukin-6 (Interleukin 6)IBA 11/2019
1	Interleukin-8 (Interleukin 8)IBA 11/2019
1	MicroRNAs (MicroRNA)IBA 08/2019
1	AlbuminsIBA 01/2019
1	Fluorescent Dyes (Fluorescent Probes)IBA 01/2019
1	mitoquinoneIBA 01/2019
1	Dextrans (Dextran)FDA Link 01/2019
1	HMGB1 Protein (HMG1)IBA 01/2019
1	Evans Blue (Blue, Evans)FDA Link 01/2019
1	Saline SolutionIBA 01/2019
1	Nucleosomes (Nucleosome)IBA 01/2019
1	Coloring Agents (Dyes)IBA 01/2019
1	Mitochondrial DNA (mtDNA)IBA 01/2019
1	obeticholic acidIBA 11/2018
1	Blood Proteins (Serum Proteins)IBA 10/2018
1	methacrylamideIBA 10/2018
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 03/2018
1	GoldIBA 03/2018

Therapy/Procedure

12	Photochemotherapy (Photodynamic Therapy) 09/2022 - 08/2015
7	Lasers (Laser) 06/2020 - 02/2005
7	Therapeutics 09/2017 - 12/2011
4	Laser Therapy (Surgery, Laser) 06/2020 - 07/2007
4	Ligation 10/2017 - 01/2008
3	Resuscitation 01/2019 - 12/2010
3	Hepatectomy 10/2017 - 12/2011
3	Radiotherapy 09/2017 - 05/2009
2	Transplantation 12/2015 - 09/2014
2	Drug Therapy (Chemotherapy) 12/2015 - 01/2008
2	Lower Body Negative Pressure 11/2011 - 04/2011
1	Bariatric Surgery 01/2022
1	Light Coagulation 09/2019
1	Induced Hypothermia 01/2019
1	Rewarming 01/2019
1	Denervation 01/2019
1	Intravenous Administration 10/2018
1	Dye Lasers 04/2018
1	Laparotomy 09/2017